Neuroscientific Foundations of Anesthesiology

Although the perioperative care of patients by anesthesiologists draws on diverse clinical skills, the principles of anesthesiology and pain management are rooted in the neurosciences. The Neuroscientific Foundations of Anesthesiology thoroughly examines the anesthetic modulation of the central, peripheral, and autonomic nervous systems and will help redefine anesthesiology as a fundamentally neuroscientific field. The book is organized by sections, with each focusing on a different part of the nervous system. State-of-the-art chapters written by thought-leaders in anesthesiology and neuroscience provide a novel and invaluable resource.I. INTRODUCTION; II. BRAIN; 1. Brain Anatomy of Relevance to the Anesthesiologist; 2. Cellular and Molecular Effects of General Anesthetics in the Brain; 3. The Shared Circuits of Sleep and Anesthesia; 4. Thalamocortical System and Anesthetic-induced Unconsciousness; 5. Anesthetic Modulation of Memory Processing in the Medial Temporal Lobe; 6. Neuroimaging Changes Associated with Human Acute and Chronic Pain; III. SPINAL CORD; 7. Spinal Cord Targets of Relevance to the Anesthesiologist; 8. Anesthetic-Induced Immobility; 9. Mechanisms of Spinal Analgesia; IV. PERIPHERAL NERVOUS SYSTEM; 10. Peripheral Nervous System: Anatomy and Function; 11. The Neurobiology of Incisional Pain; 12. Sequelae of Nerve injury: Neuropathic Pain and Complex Regional Pain Syndrome; V. AUTONOMIC NERVOUS SYSTEM; 13. The Autonomic Nervous System; 14. Anesthetic Pharmacology of the Autonomic Nervous System; VI. NEUROMUSCULAR JUNCTION; 15. Review of neuromuscular junction anatomy and function; 16. Pharmacology of Neuromuscular Blockers; 17. Anesthesia and Disorders of the Neuromuscular System; VII. NEURAL TOXICITY INDUCED BY ANESTHETICS; 18. Anesthesia-mediated neurotoxicity; 19. Post-Operative Cognitive Disorders; 20. Anesthesia and Neurodegenerative Disorders; INDEX