Cancer in Pregnancy and Lactation

Cancer in pregnancy presents physicians with a serious and ethical challenge, yet the sources of concise data and guidance for the management of this disease are scarce. The Motherisk program, based at the Hospital for Sick Children, Toronto, is dedicated to addressing this problem. Cancer in Pregnancy and Lactation: The Motherisk Guide tackles this subject by providing evidence-based information needed to address the complex issues of maternal diagnosis, management, treatment, prognosis and long-term impact on the unborn child. Based on the research by members of the international Consortium of Cancer in Pregnancy Evidence (CCoPE) this book provides physicians with the core knowledge required to make sound clinical decisions in the face of sometimes conflicting interests. Co-edited by recognized experts in the field with over 25 years' experience, this comprehensive volume is essential reading for all maternal-fetal medicine physicians, obstetricians, neonatologists, oncologists and pharmacologists.Preface; Part I. Specific Tumors During Pregnancy: 1. Bone malignancies in pregnancy Michael Lishner and Alla Osadchy; 2. Breast cancer and pregnancy Liat Mlynarsky and Michael Lishner; 3. Cervical cancer during pregnancy Asnat Walfisch; 4. Hepatocellular carcinoma Parvaneh Yazdani-Brojeni and Michael Lishner; 5. Hodgkin's lymphoma in pregnancy David Pereg and Michael Lishner; 6. Intracranial tumours in pregnancy Michael Lishner and Geert W. 't Jong; 7. The treatment of acute and chronic leukemia during pregnancy Tali Shapira-Rotenberg and Michael Lishner; 8. Lung cancer and pregnancy Hisaki Fujii; 9. Malignant melanoma and pregnancy Michael Lishner and Michael P. Tan; 10. Non-Hodgkin's lymphoma during pregnancy David Pereg and Michael Lishner; 11. Ovarian tumors and pregnancy Rinat Hackmon; 12. Thyroid cancer and pregnancy Michael P. Tan; Part II. Fetal Effects of Cancer Treatments and Interventions: 13. Pregnancy and radiation Eyal Fenig; 14. Chemotherapy during pregnancy Israel Mazin, David Pereg and Michael Lishner; 15. Non-obstetrical surgical interventions during pregnancy Bi Lan Wo, Angela Mazzolli and Alon Shrim; Part III. Management of Maternal Complications During Treatment: 16. Management of complications associated with cancer or antineoplastic treatment during pregnancy Michael P. Tan; 17. Management of nutritional problems in the pregnant cancer patient Deborah A. Kennedy; 18. Pharmacological and non-pharmacological treatment of chemotherapy-induced nausea and vomiting Caroline Maltepe; 19. Fertility considerations and methods of fertility preservation in patients undergoing treatment for cancer Avi Leader; Part IV. Long Term Effects of In Utero Exposure on Children: 20. Long term neurodevelopment of children exposed in utero to treatment for maternal cancer Irena Nulman, Claire Tobias and Elizabeth Uleryk; 21. Fertility of children exposed in utero to chemotherapy Tali Schechter and Ronen Loebstein; 22. Lactation and cancer chemotherapy Taro Kamiya and Shinya Ito; 23. Breast cancer and pregnancy: critical review of the effects of prior and subsequent pregnancy on the prognosis of young women with breast tumor Nava Siegelmann-Danieli and Ronen Loebstein; 24. Effects of the placenta of metastatic breast cancer Shelly Tartakover-Matalon, Liat Drucker and Michael Lishner; Index.