Organ Transplantation

Organ Transplantation: A Clinical Guide covers all aspects of transplantation in both adult and pediatric patients. Cardiac, lung, liver, kidney, pancreas and small bowel transplantation are discussed in detail, as well as emerging areas such as face and pancreatic islet cell transplantation. For each organ, chapters cover basic science of transplantation, recipient selection, the transplant procedure, anesthetic and post-operative care, and long-term follow-up and management of complications. Important issues in donor selection and management are also discussed, including recruitment and allocation of potential donor organs and expanding the donor pool. Summary tables and illustrations enhance the text, and long-term outcome data are provided where available. Written by expert transplant surgeons, anesthetists and physicians, Organ Transplantation: A Clinical Guide is an invaluable multidisciplinary resource for any clinician involved in transplantation, providing in-depth knowledge of specialist areas of transplantation and covering the full range of management strategies. '... provides an excellent overview of modern transplantation medicine. The increasing number of organ recipients and their improved longevity means that many more non-specialists will need to be aware of the considerations in such patients. As such, this book is particularly suitable for the general physician or intensivist. Similarly, with the growth in donation after circulatory death, healthcare professionals working with patients at the end of life will find this book valuable reading. The strength of this book is the breadth of its coverage coupled with an accessible level of detail.' Dr Julia Wendon, Senior Lecturer in Hepatology/Intensive Care Medicine, Kings College London, and Clinical Director of Intensive Care, Kings College Hospital, LondonPreface; Part I. Introduction: 1. Historical perspectives John Dunning and Roy Calne; 2. Immunological principles of acute rejection Fadi G. Issa, Ryoichi Goto and Kathryn J. Wood; 3. Immunosupression: past, present and future Robert Gaston and Vineeta Kumar; 4. Major complications: 4A. Cancer Bimalangshu R. Dey and Thomas Spitzer; 4B. Pathology of chronic rejection Yael B. Kushner and Robert B. Colvin; 4C. Infection Camille Nelson Kotton; 5. Organ donor management and procurement David Zaas; Part II. Heart: 6. Recipient selection Jayan Parameshwar and R. V. Venkateswaran; 7. Donor heart selection Jonathan G. Zaroff and Kiran K. Kusch; 8. Ventricular assist devices Steven S. L. Tsui and David G. Healy; 9. Surgical procedure D. P. Jenkins and R. V. Venkateswaran; 10. Management during surgery Kate Drummond and Andrew Klein; 11. Postoperative care and early complications Mandeep R. Mehra; 12. Long-term management and outcomes Clive J. Lewis and Harikrishnan Parthasarathy; 13. Pediatric heart transplantation Michael Burch and Jacob Simmonds; Part III. Lung and Heart-Lung Transplantation: 14. Recipient selection Jasmir Parmar; 15. Live donor lobar lung donation Hiroshi Date; 16. Surgical procedure Faruk Ozalp, Tanveer Butt and Stefan V. B. Schueler; 17. Management during surgery Peter Slinger; 18. Postoperative care and early complications Leo Ginns; 19. Long-term management and outcomes Paul Corris; 20. Pediatric lung transplantation Samuel Goldfarb and Stuart C. Sweet; Part IV. Liver: 21. Recipient selection Alex Gimson; 22. Living donor live transplantation Koji Hashimoto, Cristiano Quintini and Charles Miller; 23. Surgical procedure Neville Jamieson and Simon Harper; 24. Perioperative care and early complications John Klinck and Andrew Butler; 25. Long-term management and outcomes Graeme Alexander and William Gelson; 26. Pediatric liver transplantation Giorgina Mieli-Vergani and Hector Vilca-Melendez; Part V. Kidney: 27. Recipient selection Ernest I. Mandel and Nina Tolkoff-Rubin; 28. Sensitization of kidney transplant recipients Nick Pritchard; 29. Live donor kidney donation Arthur Matas and Hassan N. Ibrahim; 30. Surgical procedure Paul Gibbs; 31. Perioperative care and early complications John Forsythe and Lorna Marson; 32. Long-term management and outcomes John Firth and S. Mulroy; 33. Pediatric kidney transplantation Khashayar Vakili and Heung Bae Kim; Part VI. Other Abdominal Organs: 34. Pancreatic transplantation Dixon B. Kaufman; 35. Pancreatic islet transplantation James F. Markmann and Heidi Yeh; 36. Intestinal transplantation Stephen Middleton, Simon M. Gabe, Neville Jamieson and Andrew Butler; Part VII. Other: 37. Composite tissue allotransplantation: face transplantation Maria Siemienow and Can Ozturk; 38. Hematopoietic stem cell transplantation Charles Crawley and Thomas Spitzer; 39. Corneal transplantation Frank Larkin and Yvonne Luo; Part VIII. The Transplant Service: 40. UK and European perspective - legal and operational framework Chris Rudge and Alex Rahmel; 41. US perspective - legal and operational framework Frank Delmonico, Walter Graham and Richard Luskin; 42. Conclusions Clive J. Lewis; Index.